Jelena Jankovic won her first match at the the Copa Colsanitas in Bogota, but second seed Alice Cornet exited in the second round.
Serbian Jankovic was a 6-4 5-7 6-2 winner over in the first round against American Julia Cohen in a mammoth encounter that topped three hours and 18 minutes.
Colombian wildcard Marian Duque-Marino also booked a place in the second round with a 6-3 3-6 6-4 success over Estrella Cabeza Candela.
There was bad news for Cornet, though, as she failed to make the third round. Brazilian qualifier Teliana Pereira was her conqueror in a 7-5 6-7 (2/7) 6-2 upset.
Eighth seed Timea Babos was also ousted in the second round by Luxembourg's Mandy Minella, who claimed a decisive 6-4 6-1 success.
Maria-Teresa Torro-Flor will also line-up in round three after a 7-6(3) 6-3 triumph over Mathilde Johansson.