Super Eagles striker Odion Ighalo's double for Changchun Yatai was not enough as his side lost 3 - 2 to Obafemi Martins’ Shanghai Shenhua.
Ighalo side, who were playing at home, conceded the opening goal in the 14th minute after Junmin Xu fed Fredy Guarin whose shot ended in the back of the net.
Shuai Li fouled Odion Ighalo in the 18-yard box in the 39th minute and the former Watford striker stepped up to score his first goal in the Chinese league.
The Nigerian scored his second goal to put Yatai in the lead in the 50th minute after capitalising on a cross from Marinho.
Yunding Cao equalized for the visitors with an effort from outside the 18-yard-box.
Ighalo was injured and taken off the field to receive medical treatment in the 73rd minute to be replaced by Zhenyu Du.
Shenhua scored the winner in the 88th minute, when Nigerian striker Obafemi Martins fed Giovanni Andres Moreno to break the heart of Yatai.
The defeat leaves Changchun Yatai bottom of the league with just one point from five games. Shanghai Shenhua are sixth with seven points.